It is administered intravenously through a vein or by injection into a. Maxipime exists only in the form of injections and iv infusions and may be administered only intramuscularly or intravenously. Cefepime was not associated with adverse developmental outcomes in rats, mice, or rabbits when administered parenterally during period of organogenesis. Cefepime is an antibiotic used to treat a wide variety of bacterial infections. Maxipime should be administered at the same time each day and following the completion of hemodialysis on hemodialysis days see table 2. Cefepime is licensed for adults and children as young as two months old with certain bacterial infections. Find its price or cost, dose, when to use, how to use, side effects, adverse effects, substitutes. Side effects of maxipime cefepime hydrochloride for injection. Nov 30, 2009 zyloprim is known chemically as 1,5dihydro4 hpyrazolo 3,4dpyrimidin4one. Animal data suggest that cefepime penetrates into the cerebrospinal fluid csf when the meninges are inflamed. Cefepime as empirical peritoneal dialysisassociated peritonitis. Treatment of uncomplicated skin and skin structure infections. Therefore, maxipime is administered only in health facilities by trained healthcare staff.
To avoid adverse drug events, dosage adjustments are. See patient package insert in shipping carton for complete. It is possible for someone to receive too much maxipime cefepime. This emedtv page explores this topic, including a list of some offlabel unapproved uses for cefepime and an explanation on how the drug works. Our maxipime side effects drug center provides a comprehensive view of.
Maxipime powder for solution for injection drug summary. Cefepime is a drug used in people who have certain types of bacterial infections. The dosage is based on your medical condition and response to treatment. Ceftazi dime and cefepime are the only two antipseudomonal. Maxipime powder for solution for injection drug information. Cefepime has an extended spectrum of activity against grampositive and gramnegative bacteria, with greater activity against both types of organism than thirdgeneration agents. The dose of maxipime is determined by a physician and is based on the type of. In this indication it is essential that metrodinazole also be administered. Biochemicals, cefepime, histopathology, nephrotoxicity, rats.
This is not a complete list of side effects and others may occur. Side effects of maxipime cefepime hydrochloride for. If your symptoms do not improve within a few days, or if they become worse, check with your doctor. Cefepime injection in the three tested doses caused renal tubular, glomerular and vascular changes. Maxipime cefepime dosing, indications, interactions. Cefepime, dosage, effects, pharmacokinetics, resistance. The pharmacokinetics of cefepime are unaltered in patients with impaired hepatic function who received a single 1g dose.
Approximately 16% to 19% of the circulating drug is proteinbound. However, the significance of these findings in routine clinical use is not known. Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intraabdominal infections. Cefixime is an oral thirdgeneration cephalosporin antibiotic used for primarily upper respiratory infecions. Clinical pharmacology of cefepime in infants and children. Proper use of maxipime cefepime injection route a nurse or other trained health professional will give you or your child this medicine. Oct 02, 2018 maxipime can pass into breast milk and may harm a nursing baby. A package insert is a document included in the package of a medication that provides information about that drug and its use. It is distributed into most body tissues and fluids.
Cefepime injection maxipime side effects, medical uses. Maxipime is a sterile, dry mixture of cefepime hydrochloride and larginine. For prescription medications, the insert is technical, providing information for medical professionals about how to prescribe the drug. Maxipime synonyms, maxipime pronunciation, maxipime translation, english dictionary definition of maxipime. An overview of possible side effects, dosing tips, and safety precautions is also included. Cefepime is a fourthgeneration cephalosporin antibiotic. It also outlines some of the various treatment methods that are available. To use maxipime properly, you must follow all instructions given by your doctor. Maxipime dosage when determining your dosage of maxipime, your healthcare provider will take your weight, age, and the reason you are using the drug into consideration, among other factors.
Cefepime is administered intravenously and intramuscularly. Decision analysis modelling of costs and outcomes following. This medication belongs to a class of drugs known as cephalosporin antibiotics. A nurse or other trained health professional will give you or your child this medicine. The dosage of maxipime for hemodialysis patients is 1 g on day 1 followed by 500 mg every 24 hours for the treatment of all infections except febrile neutropenia, which is 1 g every 24 hours. Maxipime cefepime hydrochloride this product information is intended only for residents of the united states. A maxipime vial contains 500 mg, 1g or 2g of cefepime activity in the form of a sterile mix of cefepime dihydrochloride monohydrate and larginine. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for dilantin phenytoin. Rarely this edema may cause extreme discomfort which is not relieved by rest. A maxipime overdose is more likely to cause problems in people who have poorly functioning kidneys, as the kidneys remove this medication from the body. Maxipime cefepime hydrochloride is a broadspectrum cephalosporin antibiotic used to treat many kinds of bacterial infections, including severe or lifethreatening forms. The dosage is based on your medical condition and response. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions.
Infectious diseases pharmacotherapy for children with cystic fibrosis. Cefepime injection is used to treat many kinds of bacterial infections, including severe or lifethreatening forms. Cefepime dosing regimens in critically ill patients receiving. Maxipime cefepime hydrochloride, usp for injection fda. Maxipime 2 g injection composition maxipime cefepime hydrochloride for injection is a cephalosporin antibiotic intended for intramuscular or intravenous administration.
Cefepime is used to treat a wide variety of bacterial infections. Treatment of complicated intraabdominal infections. Nov 01, 2019 maxipime for injection is supplied for intramuscular or intravenous administration in strengths equivalent to 500 mg, 1 g, and 2 g of cefepime. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, iv tubing, and other items used. Broad spectrum against gram pos, gram neg coverage infuse over 30 mins, do not infuse thru same iv line as calcium containing iv solutions including lr and tpn clindamycin cleocin 600 mg in ns 50 ml iv. The usual dosage is 12 grams of maxipime applied two or three times daily. Maxipime cefepime hydrochloride for injection side effects. It is given by an intravenous or intramuscular injection, usually once every 8 or 12 hours. Maxipime cefepime hydrochloride injection, powder, for. Oct 02, 2018 cefepime is injected into a vein through an iv.
This medication is given by injection into a muscle or vein as directed by your doctor. In these instances, a short course of diuretic therapy may provide relief and be. Jul 09, 2015 cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intraabdominal infections. Zyloprim is known chemically as 1,5dihydro4 hpyrazolo 3,4dpyrimidin4one. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for dilantin phenytoin skip to. Package inserts for prescription drugs often include a separate document called a patient package insert with. Cefepime maxipime side effects, dosage, interactions.
Curriculum free in a few words free in practice policy forum. Fda prescribing information for maxipime cefepime hydrochloride for injection. Maxipime cefepime hydrochloride dose, indications, adverse. Drug maxipime 1g 1 injection cefepime price list or. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information continuing medication education full pi cme, medication guides, risk evaluation and mitigation strategies rems summaries, rems continuing medication. It is a xanthine oxidase inhibitor which is administered orally. Severe utis due to escherichia coli or klebsiella pneumoniae. Our maxipime side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for maxidex dexamethasone.
The impact of adding a charge for an infectious disease consultation, as. Dailymed aztreonam injection, powder, lyophilized, for solution. Cefepime treatment results in the lowest average cost per patient when used as. Cefepime is a cephalosporin sef a low spor in antibiotic. Cefepime must be given slowly, and the iv infusion can take about 30 minutes to complete. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information continuing medication education full pi cme, medication guides, risk evaluation and mitigation strategies rems summaries, rems continuing medication education rems cme, and.
Maxipime for injection is supplied for intramuscular or intravenous administration in strengths equivalent to 500 mg, 1 g, and 2 g of cefepime. Maxipime for injection is a sterile powder of cefepime in vials for reconstitution, available in 0. Maxipime cefepime hydrochloride, usp for injection for. Maxipime definition of maxipime by the free dictionary. Maxipime information, side effects, warnings and recalls. Cefepime is the generic form of the brandname drug maxipime, which is used to treat bacterial infections such as urinary tract infections, pneumonia, and skin infections.
Clavulanic acid and its salts is an inhibitor of the enzyme betalacatamase which, produced by bacteria, could inhibit the activities of beta lactam antibiotics like cefixime. A 2007 metaanalysis suggested when data of trials were combined, mortality was increased in people treated with cefepime compared with other. This medicine is given as a shot into a muscle or into a vein. Cefepime maxipime side effects, dosage, interactions drugs. Nonsteroidal antiinflammatory drugs in some patients, the administration of a nonsteroidal anti. Maxipime must be given slowly, and the iv infusion can take about 30 minutes to complete. Cefepime maxipime 2g in d5w 100 ml ivpb 2 g 200 mlhr ivpb.
Oct 11, 2019 a tissue penetration is regarded as essential to therapeutic efficacy, but specific tissue levels have not been correlated with specific therapeutic effects the concentration of aztreonam in saliva at 30 minutes after a single 1 g intravenous dose 9 patients was 0. Maxipime fda prescribing information, side effects and uses. Maxipime is indicated in paediatric patients over 2 months of age for the treatment of the infections listed below when caused by susceptible bacteria. This part of the emedtv web site describes some of the possible effects of an overdose on this drug.
Cefepime for gramnegative bacteremia in longterm hemodialysis. Maxipime cefepime hydrochloride for injection side. Nov 28, 2019 maxipime is injected into a vein through an iv. Maxipime and other antibacterial drugs, maxipime should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Pronunciation of maxipime with 2 audio pronunciations and more for maxipime.
This medication is known as a cephalosporin antibiotic. A broadspectrum cephalosporin antibiotic, c19h24n6o5s2, used in its hydrochloride form to treat a variety of infections, including skin and urinary. Maxipime cefepime hydrochloride, usp is a semisynthetic, broad spectrum, cephalosporin antibiotic for parenteral administration. Drug maxipime 2g 1 injection cefepime price list or. This emedtv web page examines how this antibiotic works to kill bacteria. Dailymed aztreonam injection, powder, lyophilized, for. Refer to the package insert for lithium preparations before use of such preparations with hydrodiuril. Urinary tract infections, both complicated, including pyelonephritis. Each scored white tablet contains 100 mg allopurinol and the inactive ingredients lactose, magnesium stearate, potato starch, and povidone.
243 1494 382 832 1228 1441 1100 793 1348 327 316 1478 404 629 140 231 577 144 233 9 267 1093 1575 136 108 268 321 777 938 1487 81 118 392